National Center for Complementary and Alternative Medicine (NCCAM) invites eligible United States small business concerns (SBCs) to submit Small Business Technology Transfer (STTR) grant applications. United States SBCs that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH awarding components identified in this FOA are encouraged to submit STTR grant applications in response to identified topics (see PHS 2016-2 SBIR/STTR Program Descriptions and Research Topics for NIH.) This FOA will utilize the R41/R42 Small Business Technology Transfer (STTR) Grant – Phase I, Phase II, and Fast-Track applications.